### BARBAROS ÇETİN

#### Professor

#### Address

Department of Mechanical Engineering

Bilkent University

06800 Bilkent, Ankara

#### Office

EA124

#### Phone

+90 (312) 290-2108

#### Web Site

http://me.bilkent.edu.tr/?page_id=1045&nvaf_id=9&lang=en

### BIOGRAPHY

Dr. Barbaros Çetin received his MS from Department of Mechanical Engineering at Middle East Technical University, and PhD from the Department of Mechanical Engineering at Vanderbilt University. His MS research was on the analysis of convective heat transfer inside microchannels under the supervision of Prof. Dr. Hafit Yüncü and Prof. Dr. Sadık Kakaç. His PhD research was on the development of lab-on-a-chip technology for the separation of microparticles and cells under the supervision of Prof. Dr. Dongqing Li. Prior to joining Bilkent University, he worked at the Middle East Technical University-Northern Cyprus Campus Mechanical Engineering as a faculty member. He joined Bilkent University Mechanical Engineering Department in 2011, and initiated the **Bilkent University Microfluidics & Lab-on-a-chip Research Group.** Dr. Çetin has completed TÜBİTAK 3501, 1001 and 1003 projects. Dr. Çetin has published many research articles in prestigious journals including Nature, Electrophoresis, Biomicrofluidics, Microfluidics and Nanofluidics, Electrochimica Acta, Int. J. Heat and Mass Transfer, Int. J. Thermal Science, ASME J. Heat Transfer.

Curriculum Vitae | Publons | ORCID | Google Scholar**Dr. Çetin is the recipient of the following awards:**

- 2018 Science Academy Association Distinguished Young Scientist Award (BAGEP)

- 2017 METU Prof. Dr. Mustafa N. Parlar Research Incentive Award

- 2017 Outstanding Young Scientist Award of the Turkish Academy of Sciences (TÜBA-GEBİP)

- 2015 Billkent University Distinguished Teaching Award

### ACADEMIC EXPERIENCE

- Professor, Bilkent University, Türkiye (2024--Present)

- Associate Professor, Bilkent University, Türkiye (2018--2024)

- Assistant Professor, Bilkent University, Türkiye (2011--2018)

- Assistant Professor, Middle East Technical University--Northern Cyprus Campus, TRNC (2010--2011)

- Instructor Dr., Middle East Technical University--Northern Cyprus Campus, TRNC (2009--2010)

- Research Assistant, Vanderbilt University, USA (2006--2009)

- Research Assistant, Middle East Technical University, Türkiye (2002--2006)

### EDUCATION

B.S. METU, Mechanical Eng. (2002)

M.S. METU, Mechanical Eng. (2005)

Ph.D. Vanderbilt University, Mechanical Eng. (2009)

### RESEARCH

My research interests and accomplishments focus on two tracks: (i) microfluidics for biomedical/chemical applications, and (ii) micro-scale heat transfer. In both topics, there are important research questions from both scientific and application point of view. In my research, basically I have been concentrating on scientific problems which will eventually lead to a solution of challenging engineering problems and/or improved design (or performance) of engineering systems within the context of these topics.

**Microfluidics for Biological and/or Chemical Applications **

For biomedical and chemical analysis in microfluidic systems, there are some fundamental operations (i.e. unit operations) such as separation, focusing, filtering, concentration, trapping, sorting, detection, counting, washing, lysis of bio-particles, and PCR-like reactions. A certain combination of these operations lead to a complete analysis system or a lab-on-a-chip system for a specific application. Manipulation of bio-particles is the key ingredient for the aforementioned processes. Simulation of bio-particles' trajectory inside microchannels is the key ingredient for microfluidic bio-particle manipulation. Our group together with our collaborators have been developing computational models for these kind of simulations. For the simulation of hydrodynamic and acoustic bio-particle manipulation, we have developed computational models via MATLAB interface of COMSOL Multiphysics. Implementing point particle approach in conjunction with pseudo Monte-Carlo approach, our group demonstrated that microfluidic particle manipulation can be effectively modeled in a real experimental setting for hydrodynamic and acoustic techniques. Albeit point particle approach is an effective and computationally inexpensive way for the simulation of particle motion, it is appropriate when the particle size is small compared to the channel dimensions. It is not straightforward to include any particle-wall and particle-particle interactions. Our group have been developing a computational model based on Boundary Element Method (BEM) to simulate the electro-kinetic motion of particles in microfluidic networks. We have recently concentrated on the electro-kinetic motion of the colloidal particles near conducting and non-conducting walls.In conjunction with these modeling efforts, our group have been developing microfluidic technologies for bacteria and DNA isolation, synthesis of nanoparticles.**Micro-scale Heat Transfer **

With the development of the fabrication techniques, the channels with a size on the order of micrometers can easily be fabricated. These micrometer scale channels have become elements of micro heat exchangers, micro heat sinks, micro-sensors, and micro power generation systems. For an effective and economical design of these micro-scale thermal systems, heat transfer characteristics at micro-scale need to be well understood. Although there exists some experimental data for fluid flow, experimental data on convective heat transfer for microchannel flows is limited. Therefore, numerical and analytical models are the key ingredients to gain fundamental understanding of fluid flow and heat transfer at micro-scale. Our group developed analytical and numerical models to investigate how the scaling alter thermal characteristics of fluid flow in microchannels with different thermal boundary conditions. Our models have been followed and used as benchmark in the literature. I have extended my heat transfer research towards the modeling and experimental characterization of flat grooved heat pipes. Together with my collaborators from METU and ASELSAN, we have been developing computational model for the comprehensive modeling of grooved heat pipes. Recently, we have developed a universal computational framework for a fast and accurate modeling of heat pipes. An analysis tool based on this framework, named Heat Pipe Analysis Toolbox (H-PAT) has been presented and will be available for academic use soon.

### PROJECTS

- Analysis of single phase fluid flow and heat transfer at micro-scale
- Boundary element formulation of particle flow in a microchannel
- Computational modeling of fin-and-tube type vehicle radiators based on porous medium approach
- Development of a microfluidic device for synthesis of chitosan nanoparticles
- Analysis of single phase fluid flow and heat transfer in slip-flow regime by parallel implementation of Lattice-Boltzmann Method on GPUs
- Development and fabrication of micro-grooved heat pipes for high-flux electronic cooling applications
- Development of a lab-on-a-chip device for the manipulation of microparticles using AC-dielectrophoresis and acoustic methods
- Development of a microfluidic device for particle counting and the application of the device for the determination of the total viable count and the number of somatic cells in reference milk sample

### RELATED PUBLICATIONS

- Özer, M.B., Çetin, B. (2021). "An extended view for acoustofluidic particle manipulation: Scenarios for actuation modes and device resonance phenomenon for bulk-acoustic-wave devices,",
*J. Acoust. Soc. Am.*, v.149(4) p.2802–2812, Full Text - Aşık, M.D., Kaplan, M., Çetin, B., Sağlam, N. (2021). "Synthesis of iron oxide core chitosan nanoparticles in a 3D printed microfluidic channel",
*J. Nanopart. Res.*, v.23(3) p.62, Full Text - Sabuncu, A.C., Çetin, B., Usta, O.B., Aubry, N. (2021). "β-dispersion of blood during sedimentation.",
*Scientific Reports*, v.11(1) p.2642, Full Text - Atay, A., Topuz, A., Sarıarslan, B., Yıldırım, Y., Charmet, J., Couling, K., Çetin, B. (2021). "Flow rate-controlled pipetting for microfluidics: second-generation flexible hydraulic reservoir (FHRv2)",
*Microfluid. Nanofluid.*, v.25(3) p.1-10, Full Text - Çetin, B., Kuşcu, Y.F., Çetin, B., Tümüklü, Ö., Cole, K.D. (2021). "Semi-analytical source (SAS) method for 3-D transient heat conduction problems with moving heat source.",
*Int. J. Heat Mass Trans.*, v.165 p.120692, Full Text - Akkuş, Y., Çetin, B., Dursunkaya, Z. (2020). "A theoretical framework for comprehensive modeling of steadily fed evaporating droplets and the validity of common assumptions",
*Int. J. Thermal Sciences*, v.158 p.106529, Full Text - Şahin, M.A., Çetin, B., Özer, M.B. (2020). "Investigation of effect of design and operating parameters on acoustophoretic particle separation via 3D device-level simulations",
*Microfluid. Nanofluid.*, v.24(8) p.1-18, Full Text - Rasooli, R., Çetin, B. (2019). "An extended Langhaar's solution for two-dimensional entry microchannel flows with high-order slip",
*Mathematics Applied to Engineering, Modelling, and Social Issues (Editors: Frank Smith, Hemen Dutta and John N. Mordeson), Springer*p.189-212, Full Text - Çelebi, A.T., Çetin, B., Beşkök, A. (2019). "Molecular and Continuum Perspectives on Intermediate and Flow Reversal Regimes in Electroosmotic Transport",
*J. Physical Chemistry C*, v.123(22) p.14024-14035, Full Text - Düven, G., Çetin, B., Kurtuldu, H., Gündüz, G.T., Tavman, Ş., Kışla, D. (2019). "A portable microfluidic platform for rapid determination of microbial load and somatic cell count",
*Biomed. Microdev.*, v.21(3) p.49, Full Text - Kibar, G., Çalışkan, U., Erdem, Y., Çetin, B. (2019). "One-pot synthesis of polyhedral oligomeric silsesquiox- ane (POSS) microparticles in a microfluidic chip", Full Text
- Atay, A., Sarıarslan, B., Kuşcu, Y.F., Akkuş, Y., Saygan, S., Gürer, T., Çetin, B., Dursunkaya, Z. (2019). "Experimental dryout characterization of commercial sintered and grooved heat pipes",
*J. Thermal Science & Technology*, v.39(2) p.101-110 - Akkuş, Y., Çetin, B., Dursunkaya, Z. (2019). "An iterative solution approach to coupled heat and mass transfer in a steadily fed evaporating water droplet",
*J. Heat Transfer*, v.141(2) p.031501, Full Text - Alijani, H., Çetin, B., Akkus, Y., Dursunkaya, Z. (2019). "Experimental thermal performance characterization of flat grooved heat pipes",
*Heat Transfer Engineering*, v.40(9-10) p.784–793, Full Text - Rasooli, R., Çetin, B. (2018). "Assessment of Lagrangian modeling of particle motion in a spiral microchannel for inertial microfluidics",
*Micromachines*, v.9(9) p.433, Full Text - Hatipoğlu, U., Çetin, B., Yıldırım, E. (2018). "A novel zero-dead-volume sample loading interface for microfluidic devices: Flexible Hydraulic Reservoir (FHR)",
*J. Micromech. Microeng.*, v.28(9) p.097001, Full Text - Oskay, Y., Çetin, B., Şerifoğlu, N., Arslan Ergül, A., Adams, M. (2018). "A novel, low-cost injection and anesthesia system for zebrafish researchers",
*Zebrafish*, v.15(2) p.85-95, Full Text - Cole, K., Çetin, B., Demirel, Y. (2018). "Semi-analytical source method for reaction-diffusion problem",
*J. Heat Transfer*, v.140(6) p.061301, Full Text, DOI: http://dx.doi.org/10.1115/1.4038987 - Düven, G., Çetin, B., Kışla, D. (2018). "Çip-üstü-laboratuvar teknolojisinin gıda mikrobiyolojisindeki uygulamaları (Lab-on-a-chip technology in food microbiology)",
*Akademik Gıda (Academic Food)*, v.16(1) p.78-87, Full Text, DOI: http://dx.doi.org/10.24323/akademik-gida.417895 - Alijani, H., Çetin, B., Akkus, Y., Dursunkaya, Z. (2018). "Effect of design and operating parameters on the thermal Performance of flat grooved heat pipes",
*Applied Thermal Engineering*, v.132 p.174-187, Full Text - Yıldıran, İ.N., Temizer, İ., Çetin, B. (2017). "Homogenization in Hydrodynamic Lubrication: Microscopic Regimes and Re-Entrant Textures",
*Journal of Tribology*, v.140 p.011701 (1-19), Full Text, DOI: http://tribology.asmedigitalcollection.asme.org/article.aspx?articleid=2628741 - Çetin, B., Güler, K.G., Aksel, M.H. (2017). "Computational modeling of vehicle radiators using porous medium approach",
*Heat Exchangers -- Design, Experiment and Simulation (Edited by Prof. S. M. Sohel Murshed, Prof. M. L. S. Matos Lopes) InTech*p.243–262, Full Text - Akkuş, Y., Tarman, H.İ., Çetin, B., Dursunkaya, Z. (2017). "Two-dimensional computational modeling of thin film evaporation",
*Int. J. Thermal Sciences*, v.121 p.237–248, Full Text - Cole, K.D., Çetin, B. (2017). "Modeling of Joule heating and convective cooling in a thick-walled micro-tube",
*Int. J. Thermal Sciences*, v.119 p.24-36, Full Text - Çetin, B., Öner, S.D., Baranoğlu, B. (2017). "Modeling of dielectrophoretic particle motion: Point particle vs finite-sized particle",
*Electrophoresis*, v.38 p.1407-1418, Full Text, DOI: http://dx.doi.org/10.1002/elps.201600461 - Kerse, C., Kalaycıoğlu, H., Elahi, P., Yavaş, S., Kesim, D., Akçaalan, Ö., Öktem, B., Çetin, B., Aşık, M., Hoogland, H., Holzwarth, R., İlday, F.Ö. (2016). "Ablation-cooled material removal with ultrafast bursts of pulses",
*Nature*, v.537 p.84-88, Full Text, DOI: http://dx.doi.org/doi:10.1038/nature18619 - Çetin, B., Özer, M.B., Çağatay, E., Büyükkoçak, S. (2016). "An integrated acoustic and dielectrophoretic particle manipulation in a microfluidic device for particle wash and separation fabricated by mechanical machining",
*Biomicrofluidics*, v.10 p.014112, Full Text, DOI: http://dx.doi.org/http://dx.doi.org/10.1063/1.4940431 - Yavuz, C., Oliaei, S.N., Çetin, B., Yeşil-Çeliktaş, Ö. (2016). "Sterilization of PMMA microfluidic chips by various techniques and investigation of material characteristics",
*J. Supercrticial Fluids*, v.107 p.114–121, Full Text, DOI: http://dx.doi.org/10.1016/j.supflu.2015.08.019 - Çetin, B., Yıldırım, E., Akay, Ş. (2016). "Mikroakışkan Sistemlerin Üretimi",
*Mikroakışkan Teknolojilerin Temelleri ve Uygulamaları (Edited by Assoc. Prof. Ö. Yeşil-Çeliktaş)*p.27–51 - Yavuz, C., Çetin, B., Yeşil-Çeliktaş, Ö. (2016). "Mikroakışkan Sistemlerin Sterilizasyonu",
*Mikroakışkan Teknolojilerin Temelleri ve Uygulamaları (Edited by Assoc. Prof. Ö. Yeşil-Çeliktaş)*p.115–137 - Yeşil-Çeliktaş, Ö., Çetin, B., Yıldırım, E. (2016). "Mikroakışkan Sistemlere Yönelik Gelecek Tahminleri",
*Mikroakışkan Teknolojilerin Temelleri ve Uygulamaları (Edited by Assoc. Prof. Ö. Yeşil-Çeliktaş)*p.199–204 - Zeinali, S., Çetin, B., Oliaei, S., Karpat, Y. (2015). "Fabrication of continuous flow microfluidics device with 3D electrode structures for high throughput DEP applications using mechanical machining",
*Electrophoresis, Special Issue on Dielectrophoresis*, v.36(13) p.1432-1442, Full Text, DOI: http://dx.doi.org/10.1002/elps.201400486 - Barışık, M., Yazıcıoğlu, A.G., Çetin, B., Kakaç, S. (2015). "Analytical solution of thermally developing microtube heat transfer including axial conduction",
*Int. Comm. Heat and Mass Transfer*, v.67 p.81-88, Full Text - Karakaya, Z., Baranoğlu, B., Çetin, B., Yazıcı, A. (2015). "A parallel boundary element formulation for tracking multiple particle trajectories in Stoke's flow for microfluidic applications",
*CMES-Computer Modeling in Engineering and Science*, v.104(3) p.227-249, Full Text - Çetin, B., Koska, K., Erdal, M. (2015). "Warpage Characterization of Microchannels Fabricated by Injection Molding",
*ASME J. Micro and Nano-Manufacturing*, v.3(2) p.021005, Full Text - Çetin, B., Li, D. (2015). "Temperature Gradient Generation and Control",
*Encyclopedia of Micro and Nanoﬂuidics (2nd Edition), Springer*p.3225-3227 - Çetin, B., Baranoğlu, B. (2015). "Boundary-Element Method in Microfluidics",
*Encyclopedia of Micro and Nanoﬂuidics (2nd Edition), Springer*p.202-213 - Çetin, B., Salemmilani, R., Li, D. (2015). "Microfluidic Rotary Pump",
*Encyclopedia of Micro and Nanoﬂuidics (2nd Edition), Springer*p.2000-2004 - Çetin, B., Salemmilani, R., D. Li (2015). "Ultrasonic pumps",
*Encyclopedia of Micro and Nanoﬂuidics (2nd Edition), Springer*p.3394-3397 - Çetin, B., Zeinali, S., Li, D. (2015). "Microfluidic Optical Devices",
*Encyclopedia of Micro and Nanoﬂuidics (2nd Edition), Springer*p.1980-1984 - Çetin, B., Zeinali, S., Li, D. (2015). "Magnetic Pumps",
*Encyclopedia of Micro and Nanoﬂuidics (2nd Edition)*p.1690-1695 - Çetin, B., Taze, S., Li, D. (2015). "Methods for Pressure Measurements",
*Encyclopedia of Micro and Nanoﬂuidics (2nd Edition), Springer*p.2828-2834 - Büyükkoçak, S., Özer, M.B., Çetin, B. (2015). "Microscale Acoustofluidics",
*Encyclopedia of Micro and Nanoﬂuidics (2nd Edition), Springer*p.2149-2158 - Büyükkoçak, S., Özer, B., Çetin, B. (2014). "Numerical modeling of acoustophoretic particle separation for microfuildics",
*Microfluid Nanofluid*, v.17(6) p.1025-1037, Full Text - Çetin, B., Zeinali, S. (2014). "Analysis of heat transfer for a low Peclet number microtube flow using second-order slip model: An extended-Graetz problem",
*J. Engineering Mathematics*, v.89(1) p.13-25, Full Text - Çetin, B., Özer, M.B., Solmaz, M.E. (2014). "Microfluidic bio-particle manipulation for biotechnology",
*Biochemical Engineering Journal*, v.92 p.63-82, Full Text - Cole, K., Çetin, B., Brettmann, L. (2014). "Microchannel heat transfer with slip flow and wall effects",
*AIAA J. Thermophysics and Heat Transfer*, v.28(3) p.455-462, Full Text - Çetin, B., Aşık, M.D., Taze, S. (2014). "Design and fabrication of a microﬂuidic device for synthesis of chitosan nanoparticles",
*ASME J. Nanotechnology in Engineering and Medicine*, v.4(3) p.031004, Full Text - Çetin, B. (2013). "Effect of thermal creep on heat transfer for a 2D microchannel flow: An analytical approach",
*ASME J. Heat Transfer, Special Issue on Microchannel Heat Transfer*, v.135(10) p.101007, Full Text - Çetin, B., Li, D. (2011). "Dielectrophoresis in microfluidics technology",
*Electrophoresis, Special Issue on Dielectrophoresis*, v.32 p.2410–2427 - Çetin, B., Bayer, O. (2011). "Evaluation of Nusselt number for a flow in a microtube using second-order slip model",
*Thermal Science*, v.15(Suppl. 1) p.103-109, Full Text - Çetin, B., Cole, K. (2011). "The effect of axial conduction on heat transfer in a liquid microchannel flow",
*Int. J. Heat and Mass Transfer*, v.54 p.2542-2549, DOI: http://dx.doi.org/10.1016/j.ijheatmasstransfer.2011.02.007 - Çetin, B., Li, D. (2010). "Lab-on-a-chip device for continuous particle and cell separation based on electrical properties via AC-dielectrophoresis",
*Electrophoresis*, v.31 p.3035-3043, DOI: http://dx.doi.org/10.1002/elps.20090007830 - Çetin, B., Yazıcıoğlu, A.G., Kakaç, S. (2009). "Slip-flow heat transfer in microtubes with axial conduction and viscous dissipation-an extended Graetz problem",
*Int. J. Thermal Sciences*, v.48 p.1673-1678, DOI: http://dx.doi.org/10.1016/j.ijthermalsci.2009.02.002 - Çetin, B., Kang, Y., Wu, Z., Li, D. (2009). "Continuous particle separation with localized AC-DEP using embedded electrodes and an insulating hurdle",
*Electrochimica Acta*, v.54 p.1715-1720, DOI: http://dx.doi.org/10.1016/j.electacta.2008.09.062 - Çetin, B., Kang, Y., Wu, Z., Li, D. (2009). "Continuous particle separation by size via AC-DEP using a lab-on-a-chip device with 3D electrodes",
*Electrophoresis*, v.30 p.766-772, DOI: http://dx.doi.org/10.1002/elps.200800464 - Çetin, B., Li, D. (2009). "Continuous particle separation based on electrical properties using AC-DEP",
*Electrophoresis*, v.30 p.3124-3133, DOI: http://dx.doi.org/10.1002/elps.20090007830 - Çetin, B., Yazıcıoğlu, A.G., Kakaç, S. (2008). "Fluid Flow in microtubes with axial conduction including rarefaction and viscous dissipation",
*Int. Comm. Heat and Mass Transfer*, v.35 p.535-544, DOI: http://dx.doi.org/10.1016/j.icheatmasstransfer.2008.01.003 - Çetin, B., Li, D. (2008). "Effect of Joule heating on electrokinetic transport",
*Electrophoresis*, v.29(5) p.994-1005, DOI: http://dx.doi.org/10.1002/elps.200700601 - Çetin, B., Travis, B.E., Li, D. (2008). "Analysis of the electro-viscous effects on pressure-driven liquid flow in a two-section heterogeneous microchannel",
*Electrochimica Acta*, v.54 p.660-664, DOI: http://dx.doi.org/10.1016/j.electacta.2008.07.008 - Çetin, B., Yuncu, H., Kakaç, S. (2006). "Gaseous flow in microconduits with viscous dissipation",
*Int. J. Transport Phenomena*, v.8(4) p.297-315, Full Text - Çetin, B., Li, D. (2008). "Microﬂuidic Rotary Pump",
*Encyclopedia of Micro and Nanoﬂuidics (1st Edition), Springer*p.1188-1189, Full Text - Çetin, B., Li, D. (2008). "Temperature Gradient Generation and Control",
*Encyclopedia of Micro and Nanoﬂuidics (1st Edition), Springer*p.1993-1994, Full Text - Çetin, B., Li, D. (2008). "Methods for Pressure Measurements",
*Encyclopedia of Micro and Nanoﬂuidics (1st Edition), Springer*p.1743-1745, Full Text - Çetin, B., Li, D. (2008). "Magnetic Pumps",
*Encyclopedia of Micro and Nanoﬂuidics (1st Edition), Springer*p.1040-1043, Full Text - Çetin, B., Li, D. (2008). "Microﬂuidic Optical Devices",
*Encyclopedia of Micro and Nanoﬂuidics (1st Edition), Springer*p.1186-1187, Full Text - Çetin, B., Li, D. (2008). "Ultrasonic pumps",
*Encyclopedia of Micro and Nanoﬂuidics (1st Edition), Springer*p.2128-2129, Full Text